Search results for "Head to head"

showing 10 items of 12 documents

AuX3-Mediated Selective Head-to-Head Dimerization of Difluoropropargyl Amides

2009

A dimerization of difluoropropargyl amides by reaction with gold(III) halides is described. A reductive elimination of a divinylgold species can be invoked to rationalize its formation. Initial studies of the unusual reactivity of these 1,4-dihalo-1,3-dienes have been performed.

Head to headStereochemistryChemistrymedicine.drug_classOrganic ChemistrymedicineChemical reductionCarboxamideReactivity (chemistry)SelectivityReductive eliminationThe Journal of Organic Chemistry
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New Dinuclear Catalysts Rh2(N−O)2[(C6H4)P(C6H5)2]2 with Imidate Ligands:  Synthesis and Isomerization from Head-to-Tail to Head-to-Head Configuration…

2001

Two new dirhodium(II) catalysts of general formula Rh(2)(N-O)(2)[(C(6)H(4))P(C(6)H(5))(2)](2) (N-O = C(4)H(4)NO(2)) are prepared, starting from Rh(2)(O(2)CCH(3))(2)(PC)(2)L(2) [PC = (C(6)H(4))P(C(6)H(5))(2) (head-to-tail arrangement); L = HO(2)CCH(3)]. The thermal reaction of Rh(2)(O(2)CCH(3))(2)(PC)(2).L(2) with the neutral succinimide stereoselectively gives one compound that according to the X-ray structure determination has the formula Rh(2)(C(4)H(4)NO(2))(2)[(C(6)H(4))P(C(6)H(5))(2)](2) (1). It corresponds to the polar isomer with two bridging imidate ligands in a head-to-head configuration. However, stepwise reaction of Rh(2)(O(2)CCH(3))(2)(PC)(2).L(2) with (CH(3))(3)SiCl and potassiu…

Head to headStereochemistryPotassiumchemistry.chemical_elementMedicinal chemistryCatalysisInorganic Chemistrychemistry.chemical_compoundchemistrySuccinimideStepwise reactionPhysical and Theoretical ChemistryEnantiomerAcetonitrileIsomerizationInorganic Chemistry
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Orthometallation reaction in dirhodium(II) compounds. Selective formation of doubly-metallated compounds with head-to-head structure

1993

Abstract The reaction of the mono-metallated compound Rh 2 (O 2 CCH 3 ) 3 [(C 6 H 4 )P(CH 3 ) (C 6 H 5 )]·2(HO 2 CCH 3 ) with PPh 3 (1:1 molar ratio) has been studied by 31 P NMR spectroscopy. The reaction yields the doubly-metallated compound Rh 2 (O 2 CCH 3 ) 2 [(C 6 H 4 ) P(CH 3 )(C 6 H 5 )]p(C 6 H 4 )P(C 6 H 5 ) 2 ]·2(HO 2 CCH 3 ) with a head-to-head (H-H) configuration. An intermediate reaction compound, not previously observed, has been spectroscopically detected in solution. Analogous intermediate compounds have been detected using P( p -CH 3 C 6 H 4 ) 3 and P( p -ClC 6 H 4 ) 3 instead of triphenylphosphine.

Inorganic Chemistrychemistry.chemical_compoundChemistryMolar ratioStereochemistryHead to headMaterials ChemistryMoleculeNuclear magnetic resonance spectroscopyCarboxylatePhysical and Theoretical ChemistryTriphenylphosphineMedicinal chemistryPolyhedron
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Head-to-head comparison of plasma cTnI concentration values measured with three high-sensitivity methods in a large Italian population of healthy vol…

2019

Abstract Background The study aim is to compare cTnI values measured with three high-sensitivity (hs) methods in apparently healthy volunteers and patients admitted to emergency department (ED) with acute coronary syndrome enrolled in a large multicentre study. Methods Heparinized plasma samples were collected from 1511 apparently healthy subjects from 8 Italian clinical institutions (mean age: 51.5 years, SD: 14.1 years, range: 18–65 years, F/M ratio:0.95). All volunteers denied chronic or acute diseases and had normal values of routine laboratory tests. Moreover, 1322 heparinized plasma sample were also collected by 9 Italian clinical institutions from patients admitted to ED with clinica…

Male0301 basic medicineprincipal component analysisvery elderlyClinical BiochemistryheparinizationBiochemistryPatient Admission0302 clinical medicineReference ValuesLimit of Detectionblood analysisTroponin IHealthy volunteers80 and overMyocardial infarctionAcute coronary syndrome; Cardiac troponins; High-sensitivity methods; Myocardial infarction; Reference population values; Acute Coronary Syndrome; Adolescent; Adult; Aged; Aged 80 and over; Blood Chemical Analysis; Female; Humans; Italy; Male; Middle Aged; Myocardium; Patient Admission; Reference Values; Troponin I; Young Adult; Emergency Service Hospital; Healthy Volunteers; Limit of DetectionReference population valuescomparative studyHigh-sensitivity methodsAged 80 and overemergency wardEmergency Servicehospital emergency servicetroponin I acute coronary syndromeSettore BIO/12clinical trialGeneral Medicinecardiac troponin 1 CLIAMiddle AgedHealthy Volunteerspriority journalItaly030220 oncology & carcinogenesisCardiac troponinFemaleAcute coronary syndromeEmergency Service HospitalAdultmedicine.medical_specialtyAcute coronary syndromecardiac muscleAdolescentHead to headheart infarctionArticleYoung AdultHospital03 medical and health sciencesbloodInternal medicinemedicinesexHumanscontrolled studyADVIA Centaurdiagnostic test accuracy studyhumannormal humanproceduresAgedbusiness.industryMyocardiumTroponin IBiochemistry (medical)reference valueEmergency departmentmedicine.diseasemajor clinical studyhospital admissionyoung adult Acute Coronary SyndromeHigh-sensitivity methodMyocardial infarctionmulticenter study030104 developmental biologySettore BIO/12 - Biochimica Clinica E Biologia Molecolare Clinicaageprotein blood levelReference valuesCardiac troponinsbusinessmetabolismBlood Chemical Analysis
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Head-to-Head Comparison of the Incremental Predictive Value of The Three Established Risk Markers, Hs-troponin I, C-Reactive Protein, and NT-proBNP, …

2020

Risk stratification among patients with coronary artery disease (CAD) is of considerable interest to potentially guide secondary preventive therapies. Cardiac troponins as well as C-reactive protein (hsCRP) and natriuretic peptides have emerged as biomarkers for risk stratification. The question remains if one of these biomarkers is superior in predicting adverse outcomes. Thus, we perform a head-to-head comparison between high-sensitivity troponin I (hsTnI), hsCRP, and N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with CAD. Plasma levels were measured in a cohort of 2193 patients with documented CAD. The main outcome measures were cardiovascular (CV) death and/or nonfata…

Malemedicine.medical_specialtymedicine.drug_classHead to headMyocardial Infarctionlcsh:QR1-502030204 cardiovascular system & hematologyBiochemistryArticlelcsh:MicrobiologyCoronary artery disease03 medical and health sciences0302 clinical medicineInternal medicineNatriuretic Peptide BrainTroponin ImedicineNatriuretic peptideHumans030212 general & internal medicineMyocardial infarctioncardiovascular diseasesMolecular BiologyAgedbiologybusiness.industryhigh-sensitivity troponin ITroponin IC-reactive proteinHazard ratioMiddle Agedmedicine.diseasePeptide FragmentsN-terminal pro-brain natriuretic peptideC-Reactive ProteinCohortbiology.proteinCardiologyFemalehigh-sensitivity C-reactive proteinprognosisbusinessBiomarkerscoronary artery diseaseFollow-Up StudiesBiomolecules
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Nebenreaktionen der radikalisch ausgelösten Cyclisierung von 2,2′-Methylen-bis(4-methyl-1,2-phenylen)-dimethacrylat

1979

2,2′-Methylene-bis(4-methyl-1,2-phenylene) dimethacrylate (1) was reacted with an excess of 2,2′-azoiso-butyronitrile (mole ratio 1:15) highly diluted in boiling benzene. The reaction products were separated by column chromatography. It was found that the 1-cyano-1-methylethyl radical induced the cyclization of 1 to yield the product of a head to tail addition (2) in 55% yield. In addition, the product of a head to head addition (3) was isolated in 4% yield. 35% of 1 reacted in the same way as it has already been observed as suppression of polymerization in the case of p-tolyl methacrylate to give the products 4 and 5. The structures of the products were confirmed by elemental analyses, by …

Mole ratioPolymers and PlasticsChemistryHead to headMethacrylateMedicinal chemistrychemistry.chemical_compoundColloid and Surface ChemistryColumn chromatographyPolymerizationYield (chemistry)Polymer chemistryMaterials ChemistryProton NMRPhysical and Theoretical ChemistryBenzeneColloid and Polymer Science
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Die intramolekulare, radikalische kopf-schwanzbzw. Kopf-Kopf-addition von Phenylen-, Naphthylen- und Biphenylenbis(methacrylat)en

1977

1,2-, 1,3- und 1,4-Phenylenbis(methacrylat) (1a), (1b) und (1c), 2,3- und 1,6-Naphthylenbis(methacrylat) (2a) und (2b) sowie 2,2′-Biphenylenbis(methacrylat) (3) wurden nach einer bekannten Vorschrift dargestellt. Setzt man stark verdunnte Losungen dieser phenolischen Bisester in siedendem Benzol einem grosen Uberschus an 2-Cyano-2-propylradikalen R. (aus AIBN) aus, so entstehen neben wenigen olig-viskosen Produkten hauptsachlich kristallisierbare Verbindungen. Sie entstanden aus der intramolekularen Addition der zwei Methacrylatgruppen und Anlagerung von zwei Radikalen R · je Molekel. 1c gab nur eine derartige Verbindung, die nach den Elementaranlysen, der rel. mol. Masse, spektroskopischen…

Polymers and PlasticsIntramolecular reactionbiologyHydroquinoneChemistryHead to headbiology.organism_classificationMedicinal chemistryHydrolysischemistry.chemical_compoundColloid and Surface ChemistryPolymer chemistryMaterials ChemistryTetraPhysical and Theoretical ChemistryDie Makromolekulare Chemie
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1988

chemistry.chemical_compoundPhenylacetylenechemistryHead to headDopingAnalytical chemistryChemical modificationInfrared spectroscopyDehydrogenationPhotochemistryElectrical conductorDie Makromolekulare Chemie, Rapid Communications
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Über die herstellung molekulareinheitlicher cyclooligomerer und ihre spaltung. III. Mitt.: Modelle für matrizenreaktionen

1967

Zunachst werden Faktoren genannt, die eine synthetische Matrizenreaktion beeinflussen konnen. Dann wird die Herstellung von Estern aus Acrylsaurechlorid mit Phenolaten molekulareinheitlicher, phenolischer Mehrkernverbindungen (durch rationale Synthese1 hergestellte Novolake) beschrieben. Es fanden sich Bedingungen, unter denen eine Polymerisation der Acrylsaurereste auf ein und dasselbe Molekul beschrankt blieb. Diese neue Polymerisationsvariante wird intramolekulare Cyclooligomerisation genannt, da die erhaltenen Produkte molekulareinheitliche Cyclooligomere sind. Eine Hydrolyse dieser Cyclooligomeren ergab molekulareinheitliche Sauren, wie die Umsetzung mit p-Nitrobenzylbromid sowie Eleme…

chemistry.chemical_compoundPolymerizationHead to headHomogeneousChemistryPolymer chemistryAcrylic acidDie Makromolekulare Chemie
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The head-to-head photodimer of indeno-indene.

2020

Irradiation of 1-(1-benzocyclobutenylidene)benzocyclobutene gives indenoindene and its head-to-head photodimer nonacyclo[9.7.7.72,10.01,11.02,10.03,8.012,17.019,24.026,31]dotriaconta-3,5,7,12,14,16,19,21,23,26,28,30-dodecaene, C32H24. The molecule is built from four essentially planar indane units attached to an elongated cyclobutane ring. In the crystal, C—H...π interactions connect molecules into layers parallel to the bc plane.

crystal structureHead to headChemistrypolycyclic hydrocarbonIndaneCrystal structureRing (chemistry)Crystallographychemistry.chemical_compoundstraincyclobutanelcsh:QD901-999lcsh:CrystallographyIndeneIUCrData
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